Biomarkers For Assessing Altherosclerotic Potential
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United States of America Patent
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Issued Date -
May 13, 2010
app pub date -
Nov 11, 2009
filing date -
Nov 11, 2008
priority date (Note) -
Abandoned
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Abstract
The invention also provides methods, apparatuses and reagents useful for predicting future atherosclerosis based on expression levels of genes selected from the set of 68 genes with differential expression in response to pioglitazone and rosiglitazone. The invention also discloses reagent sets and biomarkers for predicting progression of atherosclerosis induced by anti-diabetic therapy in a subject. In one particular embodiment the invention provides a method for predict whether a compound will induce atherosclerosis using gene expression data from sub-acute treatments.
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