Detection of Chiral Alcohols and Other Analytes
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United States of America Patent
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Issued Date -
May 13, 2010
app pub date -
Jan 29, 2008
filing date -
Jan 29, 2007
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Abandoned
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Abstract
Various methods, compounds and apparatus for the detection of analytes are provided. In one aspect, the direct oxidation of an alcohol is detected electrochemically. In another aspect, a reaction of an analyte is detected, wherein the reaction is catalysed by an enzyme and a cofactor, and wherein the cofactor comprises a moiety which is capable of acting as an electron mediator. In a further aspect, a chiral analyte is detected by resolving a enantiomeric mixture of the analyte and subsequently detecting at least one of the resolved enantiomers electrochemically. The invention is particularly relevant to the detection of alcohols, especially chiral alcohols.
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