GASTRIC RETENTION-TYPE SUSTAINED-RELEASE LEVODOPA PREPARATION
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United States of America Patent
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Issued Date -
May 6, 2010
app pub date -
Jan 10, 2008
filing date -
Jan 15, 2007
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Abandoned
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Abstract
The present invention is to provide a levodopa preparation which is able to persistently release levodopa in the stomach, has a sufficient gastric residence time, is in an easily ingestible size and is able to be easily manufactured industrially with an object of maintaining a sustained concentration of levodopa in blood. It is a gastric retentive preparation for levodopa, characterized in that, the preparation contains a gastric resident layer showing a sufficient retentive property due to a high mechanical strength in the stomach and showing a good disintegrating property in an intestinal tract in addition to a drug releasing layer containing levodopa.
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