Suppression of cancer and method for evaluating anticancer agent based on the effect of inhibiting gsk3 beta
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United States of America Patent
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Issued Date -
Apr 29, 2010
app pub date -
Jan 4, 2006
filing date -
Jan 4, 2005
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Abandoned
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Abstract
It is intended to provide a novel means of treating and diagnosing cancer by clarifying the participation of glycogen synthase kinase 3β (GSK3β) in the survival and proliferation of cancer mils. Namely, a method of suppressing the survival and proliferation of cancer cells by inhibiting the expression of GSK3β or the activity of the above-described enzyme having been activated by the phosphorylation at the 216th tyrosine residue thereof; and a method of developing a novel anticancer agent and a method of evaluating an anticancer agent based on the inhibitory effect as described above.
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