PROCESS FOR PRODUCTION OF BUPRENORPHINE PHARMACEUTICAL PREPARATION TO BE APPLIED TO MOUTH MUCOSA

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20100098757A1
SERIAL NO

12529140

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The objective of the present invention is to provide a process for producing a buprenorphine pharmaceutical preparation to be applied to mouth mucosa. The process according to the present invention for producing a buprenorphine pharmaceutical preparation to be applied to mouth mucosa includes steps of: preparing a granule for an immediate-release layer containing a buprenorphine hydrochloride crystal having 90% cumulative diameter of 200 μm or less; preparing a granule for a sustained-release layer containing a buprenorphine hydrochloride crystal having 90% cumulative diameter of 250 μm or less; and tabletting the granule for the immediate-release layer and the granule for the sustained-release layer into a two-layer tablet.

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Patent Owner(s)

Patent OwnerAddress
TOYO BOSEKI KABUSHIKI KAISHAOSAKA-SHI OSAKA 530-8230
FUSO PHARMACEUTICAL INDUSTRIES LTDOSAKA-SHI OSAKA 541-0045

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Miyasaka, Tadayo Osaka-shi, JP 7 34
Mukunoki, Fuminori Ohtsu-shi, JP 2 2

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