Mitotic Kinase Inhibitors
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United States of America Patent
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Issued Date -
Apr 15, 2010
app pub date -
Dec 2, 2005
filing date -
Dec 3, 2004
priority date (Note) -
Abandoned
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Abstract
The invention relates to inhibitors of enzymes that disrupt the assembly and function of the mitotic spindle, compositions comprising the inhibitors of Formula (I), kits and articles of manufacture comprising the inhibitors and inhibitor compositions, and methods of using the inhibitors and inhibitor compositions. The inhibitors and inhibitor compositions are useful for treating, preventing or modulating diseases in which mitotic kinesins, including kinesin-like spindle protein (KSP), may be involved; symptoms of such diseases; or the effect of other physiological events mediated by mitotic kinesins, including KSP.
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