NON-ENZYMATIC ELECTROCHEMICAL METHOD FOR SIMULTANEOUS DETERMINATION OF TOTAL HEMOGLOBIN AND GLYCATED HEMOGLOBIN
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United States of America Patent
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Issued Date -
Apr 15, 2010
app pub date -
Feb 6, 2009
filing date -
Oct 14, 2008
priority date (Note) -
Abandoned
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Abstract
A non-enzymatic electrochemical method of simultaneous measurement of hemoglobin (Hb) and percentage of glycated hemoglobin (% HbA1c) in a blood sample is disclosed. The method includes determining the total amount of hemoglobin in a sample by electrochemically measuring the voltammetric current due to iron (II) and iron (III) redox portions in hemoglobin and determining the percentage of glycated hemoglobin (HbA1c) by potentiometry. Also disclosed is a novel screen-printed electrode (SPE) strip modified for potentiometric measurement of HbA1c.
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