METHOD FOR IMPROVING THE PHARMACOKINETICS OF DRUGS METABOLIZED BY UGT2B10

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United States of America Patent

APP PUB NO 20100087493A1
SERIAL NO

12524771

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Abstract

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A method for modifying the pharmacokinetics of a pharmacologically active agent that undergoes direct N-glucuronidation by UDP-glucuronosyltransferase isoenzyme UGT2B10 in a human subject comprising administering an effective amount of an UGT2B10 modulator to said human subject. A method for identifying compounds which are directly metabolized by UGT2B10 or which act as UGT2B10 modulators is also disclosed.

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ORION CORPORATION02200 ESPOO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Finel, Moshe Helsinki, FI 1 0
Kaivosaari, Sanna Nummela, FI 1 0

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