TrkB Agonists for Treating Autoimmune Disorders
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United States of America Patent
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Issued Date -
Apr 8, 2010
app pub date -
Dec 5, 2007
filing date -
Dec 20, 2006
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Abandoned
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Abstract
Tyrosine receptor kinase (TrkB) agonists are provided for reducing leukocyte invasion of the central nervous system in autoimmune diseases such as multiple sclerosis. TrkB agonists include naturally-occurring agonists, such as NT4 and BDNF, as well as agonists such as agonist antibodies.
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