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• 15 United States
• 10 France
• 8 Japan
• 7 China
• 5 Korea
• 2 Other

Patent Owner(s)

Patent Owner	Address
BUTAMAX ADVANCED BIOFUELS LLC	ROUTE 141 & HENRY CLAY DUPONT EXPERIMENTAL STATION BUILDING 356 WILMINGTON DE 19880-0356

International Classification(s)

• C12Q:MEASURING OR TESTING PROCESSES INVOLVING ENZYMES O....
• C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....
• C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF

• 2009 Application Filing Year
• C12Q Class
• 2344 Applications Filed
• 1150 Patents Issued To-Date
• 49.07 % Issued To-Date

Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
FLINT, DENNIS	Newark, US	43	1694
# of filed Patents : 43 Total Citations : 1694
Rothman, Steven Cary	Wilmington, US	25	563
# of filed Patents : 25 Total Citations : 563
Suh, Wonchul	Hockessin, US	23	696
# of filed Patents : 23 Total Citations : 696
Tomb, Jean-Francois	Wilmington, US	39	871
# of filed Patents : 39 Total Citations : 871
Ye, Rick W	Hockessin, US	42	740
# of filed Patents : 42 Total Citations : 740

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Patent Citation Ranking

• 77 Citation Count
• C12Q Class

• 94.96 % this patent is cited more than
• 15 Age

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Maintenance Fees

Fee	Large entity fee	small entity fee	micro entity fee	due date

Fee	Large entity fee	small entity fee	micro entity fee
Surcharge after expiration - Late payment is unavoidable	$700.00	$350.00	$175.00
Surcharge after expiration - Late payment is unintentional	$1,640.00	$820.00	$410.00

Full Text

US Patent Application No: 2010/0081,154

IDENTIFICATION AND USE OF BACTERIAL [2Fe-2S] DIHYDROXY-ACID DEHYDRATASES

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Abstract

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A group of bacterial dihydroxy-acid dehydratases having a [2Fe-2S] cluster was discovered. Bacterial [2Fe-2S] DHADs were expressed as heterologous proteins in bacteria and yeast cells, providing DHAD activity for conversion of 2,3-dihydroxyisovalerate to α-ketoisovalerate or 2,3-dihydroxymethylvalerate to α-ketomethylvalerate. Isobutanol and other compounds may be synthesized in pathways that include bacterial [2Fe-2S] DHAD activity.

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Description

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