OPTICAL FLUORESCENT IMAGING
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United States of America Patent
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app pub date -
Oct 2, 2009
filing date -
Sep 19, 2000
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Abstract
Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared (NIR) spectral range. The NIR is highly sensitive for tumor detection and tracking. The application discloses targeting a tumor-enriched cell surface receptor with a ligand-conjugated fluorescent probe, which specifically allows detection of the tumor relative to the negligible animal autofluorescence.
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