NOVEL FORMS OF REBOXETINE

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United States of America Patent

APP PUB NO 20100069389A1
SERIAL NO

12553564

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to novel crystalline forms of (2R)-2-[(R)-(2-ethoxyphenoxy)-phenylmethyl]morpholine hydrochloride. In various embodiments, the novel crystalline forms may be substantially enantiopure. The preparation and characterization of the novel crystalline forms of (2R)-2-[(R)-(2-ethoxyphenoxy)-phenylmethyl]morpholine hydrochloride is also described. The invention also relates to pharmaceutical compositions containing novel crystalline forms of (2R)-2-[(R)-(2-ethoxyphenoxy)-phenylmethyl]morpholine hydrochloride, which are useful to treat and/or prevent various conditions such as nervous system and pain disorders.

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Patent Owner(s)

Patent OwnerAddress
BIONEVIA PHARMACEUTICALS INC1 NICHOLS PLACE CAMBRIDGE MA 02138

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jonaitis, David T Brookston, US 25 225
Kalofonos, Dimitris Cambridge, US 21 375
Kalofonos, Isabel Cambridge, US 13 21
Lai, Wei West Lafayette, US 26 765
Lityo, A Gracia San Diego, US 1 0
Martin-Doyle, William Newton, US 12 9
Stahly, G Patrick West Lafayette, US 65 146

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