METHODS AND MATERIALS FOR THE GENERATION OF REGULATORY T CELLS
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United States of America Patent
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Issued Date -
Mar 18, 2010
app pub date -
Feb 15, 2007
filing date -
Feb 15, 2006
priority date (Note) -
Abandoned
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Abstract
Methods are disclosed for the generation of immunosuppressive regulatory T cells. The methods can include contacting a population of CD4+CD25− T cells with a T cell receptor (TCR)/CD3 activator, a TCR co-stimulator activator, and rapamycin. Kits for the generation of immunosuppressive regulatory T cells, methods of use, and cell populations are also disclosed.
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