COMPOSITIONS AND METHODS FOR ADMINISTERING GDNF LIGAND FAMILY PROTEINS
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United States of America Patent
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Issued Date -
Mar 4, 2010
app pub date -
Feb 27, 2007
filing date -
Mar 1, 2006
priority date (Note) -
Abandoned
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Abstract
Disclosed are methods of increasing serum exposure of an administered glial cell line-derived neurotrophic factor (GDNF) ligand family protein by administering to a subject via systemic delivery (i) a GDNF ligand family protein, and (ii) an amount of heparin or heparan sulphate that increases serum exposure of the administered GDNF ligand family protein in the subject.
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