MEDICAL USES
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Issued Date -
Mar 4, 2010
app pub date -
Jun 20, 2007
filing date -
Jun 20, 2006
priority date (Note) -
Abandoned
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Abstract
The present invention provides the use of a polypeptide comprising an amino acid sequence according to SEQ ID NO: 1 (corresponding to the N-terminal 25 amino acid fragment of the human antimicrobial protein, LL-37) or a biologically active fragment, variant, fusion or derivative thereof, in the preparation of a medicament for the treatment of cancer. In particular, the inventions provides the use such polypeptides, or a fragment, variant, fusion or derivative thereof, to inhibit the proliferation and/or metastasis of cancer cells, such as breast cancer cells. The invention further comprises methods for the treatment of cancer in a patient.
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