Analysis using separation combined with chemical conversion followed by optical spectroscopy

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United States of America Patent

APP PUB NO 20100055802A1
SERIAL NO

12584345

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Abstract

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The present invention relates to the separation, quantitative measurement, and analysis of trace species using a combination of three steps in succession. First, trace species are separated from other species that are present. Second, the trace species are chemically modified to convert them into specific species that are advantageous for the third and final step. In this last step, cavity enhanced optical detection of the converted species is performed to detect and measure the concentrations of the species of interest. Because the last step has spectroscopic resolution, the concentration of isotopologues in each converted species can be determined. Further processing can provide the ratios between pairs of isotopologues, in particular the ratio of the rare isotopologues to the most abundant isotopologue.

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Patent Owner(s)

Patent OwnerAddress
PICARRO INC3105 PATRICK HENRY DRIVE SANTA CLARA CA 95054

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Crosson, Eric R Mountain View, US 19 169
Richman, Bruce A Sunnyvale, US 13 97
Saad, Nabil MR Menlo Park, US 1 11
Zare, Richard N Stanford, US 101 3790

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