MULTIMERISED HIV FUSION INHIBITORS
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United States of America Patent
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app pub date -
Jan 16, 2008
filing date -
Feb 23, 2004
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Abandoned
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Abstract
There are provided multimeric fusion proteins exhibiting anti-viral activity. The fusion proteins comprise the HR2 region of the ectodomain of the human immunodeficiency virus gp41 protein which is fused to a multimerisation domain peptide such as a trimerisation domain derived from tetranectin. The multimerised fusion proteins may be used as HIV fusion inhibitors in the treatment of AIDS.
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