METHOD FOR THE DETECTION OF INTERFERON-ASSOCIATED ANGIOSTATIC TUMORSTAGES IN COLORECTAL CARCINOMA

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United States of America Patent

APP PUB NO 20100048415A1
SERIAL NO

12516475

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Abstract

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The present invention is directed to a microarray for the detection of an angiostatic tumor stage/tumor area of colorectal carcinoma in a patient, wherein the microarray comprises gene probes capable of specifically hybridizing to predefined nucleic acids. The invention is further directed to an inhibitor or modulator of one or more of these nucleic acids, as well as to a pharmaceutical composition, comprising those inhibitors or modulators. In a further aspect, the present invention is directed to an ex vivo method for the diagnosis of an angiostatic tumor stage/tumor area in a patient suffering from a colorectal carcinoma. In a further aspect the invention is directed to predict the response of patients with colorectal carcinoma but also other diseases to therapy.

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Patent Owner(s)

Patent OwnerAddress
FRIEDRICH-ALEXANDER-UNIVERSITAET-ERLANGEN-NUERNBERGSCHLOSSPLATZ 4 ERLANGEN 91054

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Croner, Roland S Roettenbach, DE 6 7
Naschberger, Elisabeth Erlangen, DE 2 4
Stuerzl, Michael Erlangen, DE 2 4

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