PROSTATE CANCER SURVIVAL AND RECURRENCE

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United States of America Patent

SERIAL NO

12391224

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The disclosure includes the identification and use of gene expression profiles, or patterns, with clinical relevance to prostate cancer. In particular, the disclosure is based on the identities of genes that are correlated with patient survival and prostate cancer recurrence. The gene expression profiles may be embodied in nucleic acid expression, protein expression, or other expression formats and used to predict the survival of subjects afflicted with prostate cancer and to predict prostate cancer recurrence. The profiles may also be used in the study and/or diagnosis of prostate cancer cells and tissue as well as for the study and/or determination of prognosis of a patient. When used for diagnosis or prognosis, the profiles may be used to determine the treatment of prostate cancer based upon probable life expectancy and cancer recurrence and/or metastasis.

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Patent Owner(s)

Patent OwnerAddress
THE GENERAL HOSPITAL CORPORATION55 FRUIT ST BOSTON MA 02114

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Erlander, Mark G Encinitas, US 103 1015
Ma, Xiao-Jun San Diego, US 75 533
McDougal, William Scott Manchester, US 3 1
Wu, Chin-Lee Newton, US 5 10

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