INJECTABLE DRUG CARRIER COMPRISING LAYERED DOUBLE HYDROXIDE
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United States of America Patent
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Issued Date -
Feb 25, 2010
app pub date -
Jun 3, 2005
filing date -
Jun 2, 2005
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Abandoned
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Abstract
Provided is an injectable drug carrier including a non-toxic Layered Double Hydroxide (LDH) and pharmaceutically acceptable excipients. Provided is also a method of preparing the injectable drug carrier, the method including: synthesizing LDH with various compositions and controlling the size and shape of the LDH at a level that the LDH has no adverse effect in vivo. A solution obtained by dispersing the LDH in a solvent is injected in vivo. According to the method, nano-size LDH that does not affect a blood vessel in vivo can be synthesized. The LDH thus synthesized has no adverse effect in vivo even at a concentration of 400 mg/kg, and thus can contribute to establishment of a drug delivery system capable of improving the delivery efficiency of a specific drug.
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