USE OF CERTAIN CHEMICAL COMPOUNDS FOR THE INHIBITION OF THE PEPTIDYL-PROLYL CIS/TRANS ISOMERASE ACTIVITY OF CYCLOPHILINS

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United States of America Patent

SERIAL NO

12377788

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Abstract

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The present invention relates to the use of certain spiro, ketone and carboxylic acid compounds for the inhibition of the peptidyl-prolyl cis/trans isomerase activity of cyclophilins and the use of these compounds for the production of a cosmetic or pharmaceutical composition for the promotion of hair growth or for the treatment or prevention of inflammatory autoimmune diseases, of diseases caused by fungi, of bacterial infections, of viral infections, of diseases caused by parasites, protozoa or worms, of cancer, of diseases of cells, of fibrosing diseases, and of non-neoplastic changes and diseases which are attributable to prions and changes in the structure and function of cellular proteins and cells.

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Patent Owner(s)

Patent OwnerAddress
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E VMUNICH
HEINRICH-HEINE-UNIVERSITAT DUSSELDORFUNIVERSITATSSTRASSE 1 DUSSELDORF 40225

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Braun, Manfred Schifferstadt, DE 10 52
Daum, Sebastian Halle, DE 1 2
Fischer, Gunter Halle, DE 41 245
Küllertz, Gerhard Halle, DE 4 8
Schiene-Fischer, Cordelia Halle, DE 4 3

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