NOVEL GENE NORMALIZATION METHODS
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United States of America Patent
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Issued Date -
Feb 18, 2010
app pub date -
Aug 12, 2009
filing date -
Aug 12, 2008
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Abandoned
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Abstract
Measurement of gene expression relative to an endogenous control gene is prone to excessive variability between samples and even replicates. The disclosure provides methods for normalizing expression levels of a gene by scaling gene expression levels to that of the most highly expressed gene in the set of genes whose expression levels are measured, rather than a house-keeping gene.
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