Aqueous liquid preparation having improved intraocular gatifloxacin penetration

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United States of America Patent

APP PUB NO 20100035894A1
SERIAL NO

12311738

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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An object is to provide an ophthalmic aqueous preparation excellent in the retention of gatifloxacin in a tear fluid and the preparation of gatifloxacin into an aqueous humor and a conjunctiva. Another object is to prevent the formation of any precipitate and the reduction in viscosity in the aqueous liquid preparation. An aqueous liquid preparation comprising gatifloxacin, a pharmacologically acceptable salt thereof or a hydrate of gatifloxacin or the salt and at least 0.15 w/v % of xanthan gum enables to improve the retention and penetration of gatifloxacin. When at least 0.2 w/v % of sodium chloride is added to the aqueous liquid preparation, the formation of any precipitate and the reduction in viscosity in the aqueous liquid preparation can be prevented.

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Patent Owner(s)

Patent OwnerAddress
SENJU PHARMACEUTICAL CO LTD3-1-9 KAWARA-MACHI CHUO-KU OSAKA-SHI OSAKA 5410048 ?5410048
KYORIN PHARMACEUTICAL CO LTD1-3-7 OTEMACHI CHIYODA-KU TOKYO 1000004

International Classification(s)

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  • 2007 Application Filing Year
  • A61K Class
  • 9805 Applications Filed
  • 5595 Patents Issued To-Date
  • 57.07 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2007200820092010201120122013201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sawa, Shirou Hyogo, JP 28 194

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Patent Citation Ranking

  • 4 Citation Count
  • A61K Class
  • 11.97 % this patent is cited more than
  • 15 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges7303334104243222310478582826113401 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +020040060080010001200140016001800200022002400260028003000320034003600

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