COMPOUNDS AND METHODS FOR DETECTION OF CELLS
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United States of America Patent
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Issued Date -
Feb 11, 2010
app pub date -
Jan 3, 2008
filing date -
Jan 4, 2007
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Abandoned
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Abstract
The invention relates to compounds comprising an ester group for the detection in vivo of cells undergoing cell death (“dying cells”) such as, for example, cells undergoing apoptosis. These compounds are selectively retained in dying cells relative to normal cells. Thus, the compounds may be used in the detection, diagnosis and treatment of clinical conditions manifested by a cell death process.
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