IMAGING USING RADIOACTIVE MONOCATIONS IN COMBINATION WITH A RECEPTOR BINDING LIGAND THAT STIMULATES THE INFLUX OF CATIONS

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United States of America Patent

APP PUB NO 20100028912A1
SERIAL NO

12519655

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Abstract

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Rubidium (positron imaging) or Thallium (SPECT or planar imaging), in combination with a receptor binding ligand that stimulates the influx of cations. The method permits imaging of receptor-expressing tissue. However, unlike imaging methods which rely on a radiolabeled binding ligand, in the instant method the influx of the radioactive mono-cation is measured, not the binding of a radiolabeled ligand. Thus, there is a decreased likelihood of receptor saturation and potentially less radiation exposure for the patient.

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Patent Owner(s)

Patent OwnerAddress
BRACCO DIAGNOSTICS INC259 PROSPECT PLAINS ROAD BLDG H MONROE TWP NJ 08831

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Linder, Karen E Kingston, US 53 1075

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