Method for preparation of o-desmethylvenlafaxine using polythiolates

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United States of America Patent

APP PUB NO 20100016638A1
SERIAL NO

12460667

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Abstract

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This invention relates to methods of making O-desmethylvenlafaxine from venlafaxine. In the methods venlafaxine is contacted with a polythiolate. The polythiolate may be prepared from the corresponding polythiol in the presence of base. The present methods provide the O-desmethylvenlafaxine in good yields and high purity and are suitable for use on an industrial scale.

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Patent Owner(s)

Patent OwnerAddress
PLIVA HRVATSKA D O O10000 ZAGREB

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Avdagic, Amir Zagreb, HR 5 5
Hamersak, Zdenko Zagreb, HR 3 1

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