CIS-CYCLOHEXYL SUBSTITUTED PYRIMIDINONE DERIVATIVES

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United States of America Patent

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12436587

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Abstract

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Cis-cyclohexyl substituted pyrimidinone derivatives are provided, of the Formula:wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

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Patent Owner(s)

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NEUROGEN CORPORATION35 NORTHEAST INDUSTRIAL ROAD BRANFORD CT 06405

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blum, Charles A Westbrook, US 49 549
Ghosh, Manuka Madison, US 22 218
Martinez, Isamir Guilford, US 2 13
Zhang, Xuechun Guilford, US 14 126
Zheng, Xiaozhang Newton, US 158 2458

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