SPECIFIC KINASE INHIBITORS

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United States of America Patent

SERIAL NO

12536884

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Abstract

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Resorcylic acid lactones having a C5-C6 cis double bond and a ketone at C7 and other compounds capable of Michael adduct formation are potent and stable inhibitors of a subset of protein kinases having a specific cysteine residue in the ATP binding site.

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Patent Owner(s)

Patent OwnerAddress
KOSAN BIOSCIENCES INCORPORATED3832 BAY CENTER PLACE INTELLECTUAL PROPERTY DEPT HAYWARD CA 94545

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hutchinson, C Richard Cross Plains, US 11 263
Lau, Janice San Mateo, US 7 190
Reid, Ralph C San Rafael, US 17 244
Santi, Daniel V San Francisco, US 66 1488
Sundermann, Kurt F Burlingame, US 5 166

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