Biological agent detection and identification system
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United States of America Patent
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Issued Date -
Jan 7, 2010
app pub date -
Dec 21, 2004
filing date -
Dec 21, 2004
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Abandoned
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Abstract
A sample under test containing non-live and/or live particulates is subject to optical excitation on a single particle-by-particle basis or as a small group of particulates sufficient to induce a subsequent fluorescence emission that is observed for a selected period of time by a sensor, typically a photomultiplier tube. The output of the sensor is representative of the intensity or amplitude of the fluorescence emission while the decrease in that intensity or amplitude with time is representative of the decay rate of the fluorescence emission. Those particulates exhibiting a decay rate “faster” than a threshold decay rate, which is determined empirically for the class of biological agents of interest, are identified as living while those particulates exhibiting decay rate “slower” than a threshold decay rate, which is also determined empirically for the class of biological agents of interest, are identified as a non-live interferant.
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