HOMOZYGOTE HAPLOTYPE METHOD

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United States of America Patent

APP PUB NO 20090327203A1
SERIAL NO

12309994

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Abstract

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To provide a method of efficiently searching for a disease sensitivity gene and an apparatus therefor. It is intended to provide: a method of determining a homoeologous region which comprises the polymorphism marker selection step of selecting a polymorphism marker usable as the subject of the homozygote determination, the homozygote determination step of determining whether or not bases constituting a specimen DNA which is a diploid or higher are homozygous, the homozygote haplotype data acquisition step of selecting exclusively polymorphism markers determined as homozygous and acquiring homozygote haplotype data of each specimen, the homozygous region data acquisition step of comparing the above-described homozygote haplotype data of two or more specimens and acquiring common homozygous region data, and the homoeologous region determination step of determining a common homozygous region satisfying definite homoeology requirements as a homoeologous region between the corresponding specimens for each common homozygous region data; and an apparatus and a gene screening method with the use of this method.

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Patent Owner(s)

Patent OwnerAddress
SAITAMA MEDICAL UNIVERSITY38 MOROHONGO MOROYAMA-MACHI IRUMA-GUN SAITAMA 350-0495
TOMY DIGITAL BIOLOGY CO LTD3-14-17 TAGARA NERIMA-KU TOKYO 1790073

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hagiwara, Koichi Saitama, JP 18 62

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