SYNTHESIS OF 2-AMINO-SUBSTITUTED 4-OXO-4H-CHROMEN-8.YL-TRIFLUORO-METHANESULFONIC ACID ESTERS

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United States of America Patent

APP PUB NO 20090326223A1
SERIAL NO

12374354

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Abstract

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aryl group, or may together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; from a compound of formula (III): comprising the steps of: (a) removing the allyl group from the compound of formula (III) with appropriate reaction conditions to yield a compound of formula (II): and (b) reacting the compound of formula (II) with a triflating agent to yield a compound of formula (I).

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Patent Owner(s)

Patent OwnerAddress
KUDOS PHARMACEUTICALS LIMITED1 FRANCIS CRICK AVENUE CAMBRIDGE BIOMEDICAL CAMPUS CAMBRIDGE CB2 0AA
CANCER RESEARCH TECHNOLOGY LIMITEDLONDON

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Desage-El, Murr Marine Paris, FR 3 26
Golding, Bernard Thomas Tyne and Wear, GB 29 297
Griffin, Roger John Tyne and Wear, GB 34 308
Hardcastle, Ian Robert Tyne and Wear, GB 23 173
Rodriguez-Aristegui, Sonsoles Madrid, ES 1 0

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