GENE ASSOCIATED WITH ARTERIOSCLEROTIC DISEASE, AND USE THEREOF
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United States of America Patent
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Issued Date -
Dec 31, 2009
app pub date -
Apr 24, 2007
filing date -
Apr 25, 2006
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Abandoned
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Abstract
Two genes implicated in arteriosclerotic diseases such as cerebral infarction were successfully identified by performing genome-wide correlation studies using SNPs by targeting the entire genome. Polymorphic mutations that can be used to examine the presence or absence of risk factors for arteriosclerotic diseases were successfully found on the genes. Subjects can be efficiently examined for the presence or absence of risk factors for arteriosclerotic diseases using the presence or absence of the polymorphic mutations as indicators. Furthermore, methods of screening for therapeutic agents for arteriosclerotic diseases are enabled by using expression or function of the genes as index.
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