Inhibition of the Anti-FVIII Immune Response
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United States of America Patent
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Issued Date -
Dec 24, 2009
app pub date -
Dec 22, 2006
filing date -
Dec 22, 2005
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Abstract
The invention relates to a compound capable of inhibiting the endocytosis of FVIII (factor VIII) by immune system cells capable of endocytosing the antigen and to the therapeutic use of such a compound for the manufacture of a medicament for use in the treatment of hemophiliacs in order to reduce the immunogenicity of FVIII and/or increase the half-life of FVIII.
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