MODIFIED PICTET-SPENGLER REACTION AND PRODUCTS PREPARED THEREFROM
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United States of America Patent
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Issued Date -
Dec 17, 2009
app pub date -
Jun 18, 2009
filing date -
Jul 31, 2002
priority date (Note) -
Abandoned
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Abstract
A method of introducing a second stereogenic center into a tetrahydro-β-carboline have two stereogenic centers using a modified Pictet-Spengler reaction is disclosed. The method provides a desired cis- or trans-isomer in high yield and purity, and in short processes times.
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