Methods and Proteins for the Prophylactic and/or Therapeutic Treatment of Four Serotypes of Dengue Virus and Other Flaviviruses

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United States of America Patent

APP PUB NO 20090312190A1
SERIAL NO

12094503

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Abstract

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The present invention is related to the field of the pharmaceutical industry, and describes a conserved area on the surface of the E protein that can be used for the development of wide-spectrum antiviral molecules to be employed in the prophylaxis and/or treatment of infections due to Dengue Virus serotypes 1-4 and other flaviviruses. The invention also covers chimeric proteins to be used as vaccines or as a prophylactic or therapeutic treatment against the four serotypes of Dengue Virus and other flaviviruses.

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Patent Owner(s)

Patent OwnerAddress
CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIALA HABANA 11600

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Avila, Marta Ayala Ciudad De La Habana , CU 5 29
Chinea, Santiago Glay Ciudad De La Habana , CU 11 69
Cruz, Lisset Hermida Ciudad De La Habana , CU 4 31
Fleitas, Salazar Noralvis Ciudad De La Habana , CU 4 64
Gavilondo, Cowley Jorge Victor Ciudad De La Habana , CU 7 45
Gil, Valdés Jeovanis Ciudad De La Habana , CU 6 29
Guirola, Cruz Osmany Ciudad De La Habana , CU 8 64
Huerta, Galindo Vivian Ciudad De La Habana , CU 6 59
Lasa, Alexis Musacchio La Habana , CU 6 39
Martin, Dunn Alejandro Miguel Ciudad De La Habana , CU 3 34
Meireles, Rolando Paez Ciudad De La Habana , CU 2 25
Morales, Aída Zulueta Ciudad De La Habana , CU 1 25
Núnez, Mónica Sarria Ciudad De La Habana , CU 1 25
Reyes, Yuliet Mazola La Habana , CU 3 36
Roche, Diamilé Gonzáles Ciudad De La Habana , CU 1 25
Toledo, Mayora Patricia Gabriela Ciudad De La Habana , CU 3 42

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