INTERFERING IN ACTIVATION OF AN IMMUNE CELL BY INFLUENCING INTERACTION OF LAIR AND COLLAGEN

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United States of America Patent

APP PUB NO 20090304686A1
SERIAL NO

12281741

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides a method for interfering in activation of an immune cell, comprising providing a substance which specifically interacts in the binding of leukocyte-associated immunoglobulin-like receptor (LAIR) and collagen. The invention in one aspect provides a method for down regulation of activation of an immune cell. In another aspect the invention provides a method for up regulation of activation of an immune cell. The invention further provides pharmaceutical compositions and uses thereof.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITEIT UTRECHTHEIDELBERGLAAN 8 CS UTRECHT 3584
UNIVERSITAIR MEDISCH CENTRUM UTRECHTHEIDELBERGLAAN 100 UTRECHT NL-3584 CX

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lebbink, Robert Jan San Francisco , US 1 5
Meyaard, Linde De Bilt , NL 12 36

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