Use of novel biomarkers for detection of testicular carcinoma in situ and derived cancers in human samples
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United States of America Patent
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Issued Date -
Dec 3, 2009
app pub date -
Apr 21, 2005
filing date -
Apr 23, 2004
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Abstract
The present invention relates to methods and kits for identification of testicular carcinoma in situ (CIS), gonadoblastoma (a CIS-like pre-cancerous lesion found in dysgenetic gonads) and CIS-derived cancers based on at least one of the biomarkers included in the invention. It also relates to diagnosis of a subject's status of the testicular carcinoma in situ and the derived cancers based on the measurement of a relative abundance of one of the biomarkers.
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