Lipid Vesicle Composition

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United States of America Patent

APP PUB NO 20090297592A1
SERIAL NO

11920094

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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It is an object of the present invention to provide an enzyme preparation which is excellent in stability in blood (blood residence) and in transfer to a target organ (targeting property), and can be used effectively in enzyme replacement therapy or the like.This problem is solved by a lipid vesicle composition wherein vesicles composed of a lipid bilayer membrane are encapsulating an enzyme, the composition being capable of retaining stably the activity of the enzyme even outside the stable pH range of the enzyme.

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Patent Owner(s)

Patent OwnerAddress
TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCETOKYO JAPAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ito, Mai Tokyo , JP 21 349
Ito, Manabu Tokyo , JP 56 11999
Kawashima, Ikuo Kounosu-shi , JP 4 61
Mizuno, Atsushi Tokyo , JP 39 465
Ohta, Katsuji Kawaguchi-shi , JP 2 18
Sakuraba, Hitoshi Abiko-shi , JP 14 116
Tajima, Youichi Tokyo , JP 7 78
Takeoka, Shinji Tokyo , JP 70 422

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