DETECTION OF STEROID RECEPTORS ON CIRCULATING CARCINOMA CELLS AND TREATMENT
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United States of America Patent
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Issued Date -
Nov 26, 2009
app pub date -
Apr 18, 2007
filing date -
Apr 18, 2006
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Abstract
The expression of a steroid receptor from circulating carcinoma cells in a blood sample is detected by isolating the carcinoma cells from the blood sample, making an extract from the isolated carcinoma cells and then performing on the extract a sensitive immunoassay capable of detecting the carcinoma cell-associated steroid receptor. A positive result indicates the presence of the steroid receptor in the carcinoma cells. This method can be used to identify cancer patients who are likely to benefit from treatment with an endocrine therapeutic agent.
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