Methods for controlling amplification
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United States of America Patent
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Issued Date -
Nov 19, 2009
app pub date -
Nov 4, 2008
filing date -
Nov 6, 2007
priority date (Note) -
Abandoned
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Abstract
Methods of amplifying nucleic acid on a solid support are described. Beads and template, each in known concentrations, are employed so a range of template to bead ratios can be exploited. Where the beads contain primers, the template can be amplified. After amplification, non-covalently bound template is removed, so as to leave beads with extended primers (or beads with primers that were not extended).
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