Methods of Treating Degenerative Disorders With Rac 1B Inhibitor

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United States of America Patent

APP PUB NO 20090285820A1
SERIAL NO

12223520

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to compositions and methods for treating degenerative disorders. More particularly, the invention relates to methods of treating amyloïd beta peptide-related disorders, particularly Alzheimer's disease, using Rac1b inhibitors. The invention may be used in mammalian subjects, particularly human subjects, at various stages of the disease, including disease onset. The invention also provides methods of producing, identifying, selecting or optimising compounds for use in the treatment of amyloïd beta peptide-related disorders, based on a determination of the ability of a test compound to inhibit Rac1b.

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Patent Owner(s)

Patent OwnerAddress
EXONHIT THERAPEUTICS SA63-65 BLD MASSENA PARIS F-75013

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Coutadeur, Séverine Vitry Sur Seine , FR 1 0
Desire, Laurent Paris , FR 15 27
Picard, Virginie Paris , FR 5 5
Schweighoffer, Fabien Nogent Sur Marne , FR 36 135

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