FORMULATIONS FOR POORLY PERMEABLE ACTIVE PHARMACEUTICAL INGREDIENTS
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United States of America Patent
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Issued Date -
Oct 22, 2009
app pub date -
Apr 21, 2009
filing date -
Apr 22, 2008
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Abstract
The present invention relates to a pharmaceutical oral dosage form containing a poorly permeable active pharmaceutical ingredient and at least one permeability improving substance, wherein the permeability improving substance is thermostably embedded in a water-soluble matrix of a water soluble carrier, and to thermostable formulations which can be used to improve bioavailability.
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