Methods and Assays for Capture of Nucleic Acids

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United States of America Patent

APP PUB NO 20090246788A1
SERIAL NO

12408485

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure provides methods and systems for sequence specific nucleic acid target capture comprising enzymatic reactions. The present disclosure relates to a plurality of oligonucleotide probes for capture and subsequent detection of target nucleic acid sequences, using flap endonucleases, ligases, and/or additional enzymes, proteins or compounds, on substrates, for example microarray slides, and in solution formats.

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Patent Owner(s)

Patent OwnerAddress
ROCHE NIMBLEGEN INC500 S ROSA ROAD MADISON WI 53719

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Albert, Thomas Fitchburg , US 30 773
Lyamichev, Victor Madison , US 63 2976
Patel, Jigar Middleton , US 48 139

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