Control Sequences Responding to AMP and Uses Thereof
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United States of America Patent
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Issued Date -
Sep 24, 2009
app pub date -
Dec 20, 2005
filing date -
Dec 23, 2004
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a method of identifying control sequences responding to antimicrobial peptides (AMPs), to host cells expressing an AMP and comprising a control sequence of the invention operable linked to a reporter, and to a method of screening for novel AMPs or AMP-variants having improved antimicrobial activity. Particularly the present invention relates to DNA control sequences, wherein the transcriptional profiles of said control sequences are regulated by the presence of an antimicrobial polypeptide expressed inside the host cell.
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