Enzymes, cells and methods for site specific recombination at asymmetric sites

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United States of America Patent

APP PUB NO 20090217400A1
SERIAL NO

10590897

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Abstract

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The present invention relates to enzymes, compositions and methods for catalyzing asymmetric recombination of non-palindromic recombination sites in a cell free system, in isolated cells or in living organisms. The enzymes and methods of the invention are suitable for mediating specific recombinations between DNA sequences comprising specific recombination sites without being limited to strict palindromic symmetry within each recombination site.

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Patent Owner(s)

Patent OwnerAddress
STATE OF ISRAEL MINISTRY OF AGRICULTURE AGRICULTURAL RESEARCH ORGANIZATIONP O BOX 6 THE VOLCANI CENTER BET DAGAN 50250

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carmi, Nir Ramat Efal , IL 6 4
Eyal, Yoram Mesilat Zion , IL 5 7
Gidoni, David Shani-livna , IL 1 4
Santoro, Stephen W Cambridge , US 2 78
Schultz, Peter G La Jolla , US 236 4625

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