USE OF CENTRIFUGAL PARTITION CHROMATOGRAPHY FOR PURIFYING GALANTHAMINE
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United States of America Patent
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Issued Date -
Aug 27, 2009
app pub date -
Dec 6, 2005
filing date -
Dec 16, 2004
priority date (Note) -
Abandoned
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Abstract
The invention concerns the use of centrifugal partition chromatography in displacement mode for implementing a process for purifying galanthamine or its derivatives, from a starting composition, containing at least 20% of galanthamine or its derivatives. Said method comprises a step of centrifuging a combination of at least two solvents and said starting composition, for a time sufficient for purifying the galanthamine or its derivatives, said solvents being such that they form two non-miscible phases, namely an aqueous phase and an organic phase, the aqueous phase serving as mobile phase or stationary phase, the organic phase serving respectively as stationary phase or mobile phase.
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