Crystal Structure of Biotin Carboxylase (Bc) Domain of Acetyl-Coenzyme a Carboxylase and Methods of Use Thereof

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United States of America Patent

APP PUB NO 20090215627A1
SERIAL NO

11573217

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Abstract

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A crystal comprising a biotin carboxylase domain of acetyl-CoA carboxylase is described, along with a computer-based method for identifying compounds that modulates activity of acetyl-CoA carboxylase, a computer-based method for rationally designing a compound that modulates activity of acetyl-CoA carboxylase, along with compounds produced by such methods, as well as compositions and methods of use thereof.

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Patent OwnerAddress
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK412 LOW MEMORIAL LIBRARY 535 WEST 116TH STREET NEW YORK NY 10027

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Anderson, Richard Palo Alto , US 111 2502
Elich, Tedd D Durham , US 42 68
Shen, Yang New York , US 112 384
Tong, Liang Scarsdale , US 28 67
Volrath, Sandra L Durham , US 13 305
Weatherly, Stephanie C Durham , US 3 1

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