Proteomic Fingerprinting of Human IVF-Derived Embryos: Identification of Biomarkers of Developmental Potential

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United States of America Patent

APP PUB NO 20090215085A1
SERIAL NO

12162471

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention discloses biomarkers and biomarker combinations that have prognostic value as predictors of the developmental potential of individual IVF-derived human embryos. In particular, the biomarkers of this invention are useful to classify an embryo with implantation competence after uterine transfer or implantation incompetence. In addition, the biomarkers can be detected by non-invasive methods that do not harm the developing embryo. Also disclosed are kits for the prediction of developmental potential that detect the biomarkers of the invention, as well as methods using a plurality of classifiers to make a probable diagnosis of developmental potential.

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Patent Owner(s)

Patent OwnerAddress
EASTERN VIRGINIA MEDICAL SCHOOL721 FAIRFAX AVENUE SUITE 120 NORFOLK VA 23507

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bocca, Silvina Norfolk , US 1 3
Cazares, Lisa H Chesapeake , US 4 23
Oehninger, Sergio C Norfolk , US 3 4
Semmes, O John Newport News , US 4 19

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