HOST CELL LINES FOR PRODUCTION OF ANTIBODY CONSTANT REGION WITH ENHANCED EFFECTOR FUNCTION
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United States of America Patent
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Issued Date -
Aug 27, 2009
app pub date -
Aug 31, 2006
filing date -
Aug 31, 2005
priority date (Note) -
Abandoned
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Abstract
Host cell lines for biopharmaceutical production of antibodies, antibody fragments or antibody-derived fusion proteins are selected as having the capability of inducing improved cellular effector functions, e.g., Fc-medicated effector functions. The host cells are derived from the rat myeloma cell line YB2/0 and are adapted to growth in chemically-defined medium.
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