Treatment of Pain With Resiniferatoxin and Related Analogs
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United States of America Patent
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app pub date -
Jan 20, 2009
filing date -
Jul 20, 2006
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Abstract
A method of treating inflammatory pain conditions is provided that involves administering an effective amount of a TRPV1 agonist, such as resiniferatoxin, tinyatoxin and related potent agonists and their analogs, to a patient to selectively induce nerve terminal depolarization block and/or nerve terminal death in select TRPV1-containing neurons, to provide the desired pain relief without significant permanent damage to cell bodies of the select TRPV-1 containing neurons.
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